Palatal myoclonus is a rare syndrome characterized by an involuntary rhythmic movement of the soft palate, occasionally involving the muscles of pharynx, larynx, and diaphragm. Many authors reported that the clinical manifestations of this disease result from the lesion involving the dentato-rubro-olivary pathway and the inferior olivary nucleus. In general, this condition is notoriously resistant to therapies. But, several reports described improvement of palatal myoclonus during sleep or medical and surgical treatment. This 22-year-old man was exposed to noise and barotrauma. On an hour after exposure, he began to show rapid and repeatitive contraction of soft palate(60 per minute) including subjective tinnitus. Palatal myoclonus has continued during sleep and it did not respond to phenytoin, chlonazepam, valproic acid, and alprazolam. For the further treatment modality, we report a case of palatal myoclonus with a review of literature.