Aspergillus is a fungus of the Ascomycetes class that occurs worldwide and found in many of the molds on food, fruit, grain, and plant. Its ubiguitous spores, present in dust, enter the respiratory system of man where, under proper conditions, they can become pathogenic. Although its incidence is rare, with the frequent use of antibiotics, steroids, immunosuppressives and oncologic drugs the incidence of such infections seems to have increased. We experienced a case of Aspergillosis of Maxillary sinus occuring in a 30 year old female and report with a review of literature.