Histopathological Study of Vocal Nodule and Vocal Polyp |
Tae Young Hahm, MD1, Jae Ki Kim, MD1, Chang Sun Moon, MD1, Soon Rock Park, MD1, and Il Hyang Ko, MD2 |
1;Department of Otolaryngology, 2;Clinical Pathology, In-Je Medical College, Korea |
聲帶結節 및 聲帶포립의 病理組織學的 觀察 |
咸泰英1 · 金在基1 · 文昌宣1 · 朴淳錄1 · 高一香2 |
仁濟大學校 醫科大學 耳鼻咽喉科學敎室1;臨床病理學敎室2; |
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ABSTRACT |
The histopathological findings of 70 cases of vocal nodules and vocal polyps were observed. Their clinical diagnoses were vocal nodule in 6 cases, localized polyp in 61 cases and diffuse vocal polyposis in 3 cases, and the following results of microscopic examination were obtained. 1) Their stromal changes were devided respectively into polypoid stage ; 13%, polypoid with varicous stage ; 9%, varicous stage; 6%, varicous with hyaline stage ; 41% and hyaline stage ; 31% according to P.B. Szanto's classification. 2) The young vocal nodules and polyps showed mainly edema and vascular changes. In the polyp group varices, organizing thrombi and fibrinoid changes were intermixed with the early changes described above. 3) The matured nodules and old large polyps exhibited more prominent fibrinoid and hyaline degeneration associated with the early stromal changes. 4) Most of nodules and polyps were covered by the usual stratified squamous epithelium but focal hyperkeratosis, parakeratosis, acanthosis and atrophy were rather frequently observed. Hyperkeratosis was seen most frequently in 63 percent. 5) There was very mild inflammatory cell infiltration in vocal nodules and polyps comparing with those of polypoid lesions of other organs, and the fibrous change was generally parallel with the grade of inflammatory cell infiltration. 6) It is our opinion that vocal nodules and polyps present different development stages of essentially same lesion, and from a histopathological standpoint the differences between them appear to be quantative rather than qualitative. |
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