Characteristically, patients with necrotizing lymphadenitis are young women with cervical lymphadenopathy which may be tender and associated, in some cases, with fever and leukopenia. The course is invariably benign, since the lymphadenopathy resolves spontaneously, usually within 2-3 months. Histologically, the involved lymph nodes show focal, well-circumscribed, paracortical, necrotizing lesions, and abundant karyorrhectic debris, scattered fibrin deposits, aggregates of large mononuclear cells, and a paucity of plasma cells and neutrophils. Recently we experienced two cases of necrotizing lymphadenitis and report with a review of literature.
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