Since the confirmation of the reaginic antibody as IgE, there have been many studies about the pathogenesis of allergic diseases. But there are no definite theories about the pathogenesis. Especially the immunologic mechanism of antibody production remains to be proved. Recently the theory of increased production of IgE due to immunodeficiency is becomming popular. Namely the activation of B lymphocyte due to functional defect of suppressor T lymphocyte increases the serum level of the IgE. So the main goal of hyposensitization is to decrease the level of IgE by increasing the activity of suppressor T lymphocyte. Therefore I calculated the percentage of T lymphocyte and suppressor T lymphocyte in the blood to see the relationship with allergic rhinitis. The study was done in three group ; 10 allergic rhinitis patients with positive skin test, 10 allergic rhinitis patients with negative skin test and 10 controls without allergic rhinitis. I calculated the percentage of suppressor T lymphocyte with anti-OKT₈ antibody. Following results were obtained. 1) In allergic patients the percentage of T lymphocyte was higher than that of the control group. 2) There is no difference in the percentage of active form T lymphocyte in allergic patients and control group. 3) In allergic patients the percentage of suppressor T lymphocyte was lower than that of the control group. 4) In allergic patients there was no relationship in the level of T lymphocyte and suppressor T lymphocyte with the level of IgE, severity of symptoms, duration of the disease and blood eosinophilia.