This report is a retrospective review of 290 cases of histologically proved nasopharyngeal malignant tumors treated in the Dept. of Otolaryngology, Cancer Research Hospital from Dec. 1963 to Dec. 1979. The 5 years follow up data of 77 patients & several important factors affecting the prognosis are analyzed. The results were as follows. 1) Incidence rates were 0.71%. 2) There were 220 males & 70 females with sex ratio of 3.1 : 1. 3) The age distribution was from 4 to 76 and the mean age 42.2 in male, 45.1 in female and 42.9 in total. 4) The presenting symptoms were as following, neck mass 73.2%, nasal symptoms 66.2%, ear symptoms 45.5%, headache 25.9%, neurologic symptoms 14.1%. 5) The mean duration of the symptomatic period was 7.3 months. 6) Incidence of spread to continuous structures on 1st visit was as following; oropharyngeal wall 15.5%, central nerve system 14.1%, nasal cavity 9.0%, soft palate 4.1%, especially external auditory canal & mastoid 1.7% (5 cases). 7) The skull X-ray studies showing the erosion & destruction of the skull base were 27.6%. 8) Histopathologically, the malignant tumors were composed of carcinoma 81.3%, malignant lymphoma 16.2%, sarcoma 3%. 9) Incidence of distant metastasis was 18.2%. 10) Overall survival rates without regarding to stage were 19.5%. 11) As to survival rate according to sex, male had 19.3% & female had 20%, no differences of sex were observed. 12) As to survival rate according to age, group 4th decade showed better prognosis with 29.1%. 13) As to survival rate according to neck metastasis, the survival rates were 39.1% & 11.1% for patients with absent node involvement and those with nodal disease respectively. 14) There were no survivors when distant metastasis & neurologic symptoms were present. 15) Survival rates for patients with malignant lymphoma, undifferentiated cancer, squamous cell cancer, lymphoepithelioma were 26.3%, 25.0%, 18.6%, 14.3%.